The effects of antibiotics on the production of Panton-Valentine leukocidin (PVL).
نویسندگان
چکیده
منابع مشابه
Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.
We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.
متن کاملStaphylococcus aureus corneal infections: effect of the Panton-Valentine leukocidin (PVL) and antibody to PVL on virulence and pathology.
PURPOSE Community-associated methicillin-resistant Staphylococcus aureus strains expressing Panton-Valentine leukocidin (PVL) are associated with severe skin and soft tissue infections, necrotizing pneumonia, and eye infections. We determined PVL's toxicity on infected mouse and cultured human corneal epithelial cells and the role of PVL and antibody to PVL in pathogenesis of murine keratitis. ...
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BACKGROUND Regional differences in the prevalence of Panton-Valentine leukocidin (PVL) and PVL isoform-harboring strains as well as in the local population structure of Staphylococcus aureus may influence the clinical spectrum of S. aureus infections. METHODS Using a prospective collection of S. aureus isolates from northern Australia, we determined differences between infections caused by (1...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 2008
ISSN: 0022-6769,2188-2134
DOI: 10.14789/pjmj.54.480